RNA Details
Disease Name
diabetic nephropathy
Tissue
kidney
RNA Symbol
mir-155
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
dual-luciferase reporter assays; CHIP assay
Target
SIRT1
Pathway
P53 SIGNALING PATHWAY
PubMed ID
Title
Role of p53/miR-155-5p/sirt1 loop in renal tubular injury of diabetic kidney disease
Year
2018
Function
"Under high glucose conditions, over expression of miR-155 decreased the expression of lc3-ii and atg5 in human Kidney 2 (HK-2) cells."